(S)-2-Hydroxy-2-methyl-3,3,3-trifluoropropanoic acid

(S)-2-Hydroxy-2-methyl-3,3,3-trifluoropropanoic acid - Names and Identifiers

Name	(S)-3,3,3-Trifluoro-2-Hydroxy-2-Methylpropionic Acid
Synonyms	(S)-α-(Trifluoromethyl)lactic acid Methyl 3,3,3-trifluoro-2-hydroxypropanoate (+)-3,3,3-Trifluoro-2-methyl-D-lactic acid (S)-3,3,3-Trifluoro-2-hydroxy-2-methylpropionic (S)-2-Hydroxy-2-trifluoro-oro-methylpropionic acid (S)-2-Hydroxy-2-methyl-3,3,3-trifluoropropanoic acid (S)-3,3,3-TRIFLUORO-2-HYDROXY-2-METHYLPROPIONIC ACID (S)-3,3,3-Trifluoro-2-hydroxy-2-methylpropanoic acid (S)-3,3,3-Trifluoro-2-Hydroxy-2-Methylpropionic Acid (2S)-2-Hydroxy-2-methyl-3,3,3-trifluoropropanoic acid (2S)-3,3,3-trifluoro-2-hydroxy-2-methylpropanoic acid Propanoic acid, 3,3,3-trifluoro-2-hydroxy-, methyl ester Propanoic acid, 3,3,3-trifluoro-2-hydroxy-2-methyl-, (2S)-
CAS	24435-45-8
InChI	InChI=1/C4H5F3O3/c1-3(10,2(8)9)4(5,6)7/h10H,1H3,(H,8,9)/t3-/m0/s1

(S)-2-Hydroxy-2-methyl-3,3,3-trifluoropropanoic acid - Physico-chemical Properties

Molecular Formula	C4H5F3O3
Molar Mass	158.08
Density	1.532±0.06 g/cm3 (20 ºC 760 Torr)
Melting Point	110 °C
Boling Point	60-64°C 20mm
Flash Point	103.4±25.9℃
Vapor Presure	0.0042mmHg at 25°C
pKa	2.46±0.22(Predicted)
Storage Condition	Inert atmosphere,2-8°C
Sensitive	Sensitive to heat
Refractive Index	-16.5 ° (C=5, H2O)
MDL	MFCD03092898

(S)-2-Hydroxy-2-methyl-3,3,3-trifluoropropanoic acid - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.
UN IDs	UN 3261 8/PG III
Hazard Class	IRRITANT
Packing Group	III

(S)-2-Hydroxy-2-methyl-3,3,3-trifluoropropanoic acid - Introduction

(S)-3,3, Acid, also known as (S)-3,3,3-Trifluoro-2-Hydroxy-2-Methylpropionic Acid, is an organic compound. The following is a description of its nature, use, formulation and safety information:

Nature:
-Appearance:(S)-3,3, Acid is a colorless liquid.
-Molecular formula: C4H5F3O3
-Molecular weight: 148.08g/mol
-Melting point:-75 ° C
-Boiling point: 135-137 ° C
-Solubility: Soluble in water, soluble in organic solvents such as ethanol and ether.

Use:
- (S)-3,3, Acid is an important organic synthetic intermediate, commonly used in drug synthesis, Pesticide Synthesis and functional compound synthesis and other fields.
-It can be used as a raw material for the synthesis of chiral drugs and can introduce chiral carbon centers.
-It can also be used as a ligand for catalysts or stabilizers.

Method:
The preparation of (S)-3,3, Acid can be obtained by etherification reaction of sodium carbonate and (S)-2-bromopropionic Acid.

Safety Information:
- (S)-3,3, Acid is a chemical, and you should pay attention to safe operation when using it.
-May be irritating to eyes, skin and respiratory tract.
-use to maintain good ventilation conditions, avoid inhalation or contact.
-In case of contact with skin or eyes, rinse immediately with water for at least 15 minutes and seek medical help.
-It should be stored in a sealed container, away from fire and oxidizing agents.

Last Update：2024-04-09 15:17:56